University of California San Francisco

John R. Feiner - 144
John
Feiner
MD

Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Care

Address

521 Parnassus Avenue, #4C1
San Francisco, CA 94117
United States

Email: [email protected]
Fax: 415-476-9516

    Biography

    My research addresses clinical questions by studying human subjects or patients. I collaborate with other faculty in the department on my research and provide expertise in the following areas: data analysis and statistics; mathematical modeling; data acquisition programming; human studies; respiratory physiology.

    My research involvement has included multiple different projects:

    •    Accuracy of pulse oximetry, including determination of methemoglobin, carboxyhemoglobin, and the accuracy of cerebral oximetry.
    •    Organ transplantation and efforts to improve the quality of cadaveric organs.
    •    Acute normovolemic hemodilution to study the tolerance of acute anemia, as a way to examine red cell transfusion thresholds.  Additionally, we have used this model to study other issues in transfusion, including TRALI.
    •    The utility of somatosensory and motor evoked potential, which are used in major spine surgery to assess the integrity of spinal cord function.
    •    The physiology of breathholding and drug-induced apnea.
    •    High altitude physiology
    •    Clinical effects of neuromuscular blockade

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019
    University of California, San Francisco Residency School of Medicine

    Board Certifications

    American Board of Anesthesiology

    Clinical Expertise

    Kidney Transplantation

    Liver Transplantation

    Pancreas Transplantation

    Program Affiliations

    • Department of Anesthesia and Perioperative Care
    • Department of Surgery, Division of Transplantation

    Research Interests

    Hypoxic ventilatory drive at altitude

    Apnea with remifentanil and propofol

    Transfusion Related Acute Lung Injury

    Neuromonitoring in Spine Anesthesia

    Pulse oximeter accuracy

    Physiology of acute anemia

    Predictors of kidney and liver donor organ function

    View Research Profile at UCSF Clinical & Translational Science Institute

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 91
    1. Acute severe isovolemic anemia impairs cognitive function and memory in humans.
      Weiskopf RB, Kramer JH, Viele M, Neumann M, Feiner JR, Watson JJ, Hopf HW, Toy P| | PubMed
    2. Fatigue during acute isovolemic anemiain healthy, resting humans.
      Toy P, Feiner J, Viele MK, Watson J, Yeap H, Weiskopf RB| | PubMed
    3. Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1).
      Lieberman JA, Weiskopf RB, Kelley SD, Feiner J, Noorani M, Leung J, Toy P, Viele M| | PubMed
    4. Tidal volume, PaCO2, and lung injury.
      Gregory GA, Feiner J, Severinghaus JW| | PubMed
    5. Human cardiovascular and metabolic response to acute, severe isovolemic anemia.
      Weiskopf RB, Viele MK, Feiner J, Kelley S, Lieberman J, Noorani M, Leung JM, Fisher DM, Murray WR, Toy P, Moore MA| | PubMed
    6. Interactive effects of pH and temperature on N-methyl-D-aspartate receptor activity in rat cortical brain slices.
      Gray AT, Buck LT, Feiner JR, Bickler PE| | PubMed
    7. Exercise-induced VA/Q inequality in subjects with prior high-altitude pulmonary edema.
      Podolsky A, Eldridge MW, Richardson RS, Knight DR, Johnson EC, Hopkins SR, Johnson DH, Michimata H, Grassi B, Feiner J, Kurdak SS, Bickler PE, Severinghaus JW, Wagner PD| | PubMed
    8. Pulmonary hemodynamic response to exercise in subjects with prior high-altitude pulmonary edema.
      Eldridge MW, Podolsky A, Richardson RS, Johnson DH, Knight DR, Johnson EC, Hopkins SR, Michimata H, Grassi B, Feiner J, Kurdak SS, Bickler PE, Wagner PD, Severinghaus JW| | PubMed
    9. Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia.
      Bickler PE, Buck LT, Feiner JR| | PubMed
    10. Hypoxic ventilatory response predicts the extent of maximal breath-holds in man.
      Feiner JR, Bickler PE, Severinghaus JW| | PubMed