University of California San Francisco

John R. Feiner - 144
John
Feiner
MD

Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Care

Address

521 Parnassus Avenue, #4C1
San Francisco, CA 94117
United States

Email: [email protected]
Fax: 415-476-9516

    Biography

    My research addresses clinical questions by studying human subjects or patients. I collaborate with other faculty in the department on my research and provide expertise in the following areas: data analysis and statistics; mathematical modeling; data acquisition programming; human studies; respiratory physiology.

    My research involvement has included multiple different projects:

    •    Accuracy of pulse oximetry, including determination of methemoglobin, carboxyhemoglobin, and the accuracy of cerebral oximetry.
    •    Organ transplantation and efforts to improve the quality of cadaveric organs.
    •    Acute normovolemic hemodilution to study the tolerance of acute anemia, as a way to examine red cell transfusion thresholds.  Additionally, we have used this model to study other issues in transfusion, including TRALI.
    •    The utility of somatosensory and motor evoked potential, which are used in major spine surgery to assess the integrity of spinal cord function.
    •    The physiology of breathholding and drug-induced apnea.
    •    High altitude physiology
    •    Clinical effects of neuromuscular blockade

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019
    University of California, San Francisco Residency School of Medicine

    Board Certifications

    American Board of Anesthesiology

    Clinical Expertise

    Kidney Transplantation

    Liver Transplantation

    Pancreas Transplantation

    Program Affiliations

    • Department of Anesthesia and Perioperative Care
    • Department of Surgery, Division of Transplantation

    Research Interests

    Hypoxic ventilatory drive at altitude

    Apnea with remifentanil and propofol

    Transfusion Related Acute Lung Injury

    Neuromonitoring in Spine Anesthesia

    Pulse oximeter accuracy

    Physiology of acute anemia

    Predictors of kidney and liver donor organ function

    View Research Profile at UCSF Clinical & Translational Science Institute

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 91
    1. Progressive suppression of motor evoked potentials during general anesthesia: the phenomenon of "anesthetic fade".
      Lyon R, Feiner J, Lieberman JA| | PubMed
    2. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects.
      Pauli-Magnus C, Feiner J, Brett C, Lin E, Kroetz DL| | PubMed
    3. Acute isovolemic anemia does not impair peripheral or central nerve conduction.
      Weiskopf RB, Aminoff MJ, Hopf HW, Feiner J, Viele MK, Watson JJ, Ho R, Songster C, Toy P| | PubMed
    4. Heart rate increases linearly in response to acute isovolemic anemia.
      Weiskopf RB, Feiner J, Hopf H, Viele MK, Watson JJ, Lieberman J, Kelley S, Toy P| | PubMed
    5. Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia.
      Weiskopf RB, Feiner J, Hopf HW, Viele MK, Watson JJ, Kramer JH, Ho R, Toy P| | PubMed
    6. Productivity versus availability as a measure of faculty clinical responsibility.
      Feiner JR, Miller RD, Hickey RF| | PubMed
    7. Epinephrine increases the neurotoxic potential of intrathecally administered lidocaine in the rat.
      Hashimoto K, Hampl KF, Nakamura Y, Bollen AW, Feiner J, Drasner K| | PubMed
    8. Hemoglobin desaturation after succinylcholine-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers.
      Heier T, Feiner JR, Lin J, Brown R, Caldwell JE| | PubMed
    9. Subcutaneous perfusion and oxygen during acute severe isovolemic hemodilution in healthy volunteers.
      Hopf HW, Viele M, Watson JJ, Feiner J, Weiskopf R, Hunt TK, Noorani M, Yeap H, Ho R, Toy P| | PubMed
    10. Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans.
      Leung JM, Weiskopf RB, Feiner J, Hopf HW, Kelley S, Viele M, Lieberman J, Watson J, Noorani M, Pastor D, Yeap H, Ho R, Toy P| | PubMed