Biography
My research relates to the early detection and prevention of lung cancer through minimally invasive ways. My research spans translational and computational approaches as well as clinical trials.
In order to schedule an appointment with Dr Gesthalter at the UCSF Interventional Pulmonary clinic please call (415)885-3882. Please bring all available images (cat scans, PET scans) on CDs at the time of consultation to facilitate care.
Clinical Expertise
• Thoracic malignancies
• Lung nodules
• Symptom management
• Diagnostic and staging procedures
• Complex pleural effusions – ultrasound, thoracentesis, chest tubes, tunneled pleural catheters, medical thoracoscopy
• Ablative bronchoscopic techniques (cryo- surgery, electrosurgery, argon plasma coagulation (APC), cryospray, photodynamic therapy)
• Advanced bronchoscopy (electromagnetic navigation bronchoscopy (EMN), endobronchial ultrasound (EBUS), rigid bronchoscopy)
• Fiducial placement for radiation therapy
• Sarcoidosis and other non-malignant lung pathologies
• Tracheal and bronchial obstructions
• Tracheal and bronchial stent placement
Research Interests
• Lung cancer diagnostics
• Bioinformatics
• Application of minimally invasive diagnostic and therapeutic techniques
• Lung cancer screening
• Smoking cessation
• Management of lung transplant related airway and pleural disease
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Michael Stulbarg Outstanding Teacher Award | University of California San Francisco | 2023 |
Excellence in Teaching Award | University of California San Francisco - Haile T. Debas Academy of Medical Educators | 2019 |
Thoracic Oncology Assembly Abstract Scholarship | American Thoracic Society | 2016 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
BIDMC/MGH Harvard School of Medicine | Fellowship in Interventional Pulmonary Medicine | 2017 | |
Boston University School of Medicine - Division of Computational Biomedicine | Research Fellowship | 2016 | |
Boston University School of Medicine - Dept of Pulmonary & Critical Care | Fellowship in Pulmonary and Critical Care | 2015 | |
Yale School of Medicine - Dept of Internal Medicine | Residency | 2011 | |
Tel-Aviv University Sackler School of Medicine | MD | 2008 | |
Hebrew University of Jerusalem | B.Sc | 2003 |
Clinical Expertise
Thoracic Malignancies
Lung nodules
Symptom management
Diagnostic and staging procedures
Complex pleural effusions – ultrasound, thoracentesis, chest tubes, tunneled pleural catheters, medical thoracoscopy
Ablative bronchoscopic techniques (cryo- surgery, electrosurgery, argon plasma coagulation (APC), cryospray, photodynamic therapy)
Advanced bronchoscopy [Electromagnetic navigation bronchoscopy (EMN)],Endobronchial ultrasound (EBUS), Rigid bronchoscopy
Fiducial placement for radiation therapy
Sarcoidosis and other non-malignant lung pathologies
Tracheal and bronchial obstructions
Tracheal and bronchial stent placement
Foreign Languages Spoken
Research Narrative
My interest is in the early diagnosis and prevention of lung cancer through screening, behavioral interventions and chemoprevention. I have used gene-expression analysis to study the molecular profiles of patients at risk for future development of lung cancer and used these profiles to understand the effects various therapies have on the pre-malignancy biology of the lungs. This holds the potential to decrease lung cancer burden by disease aversion. Additionally, I study how to apply new diagnostic technologies that might expedite patient care in a minimally invasive way.
Research Interests
Smoking cessation
Lung cancer screening
Lung cancer diagnostics
Bioinformatics
Application of minimally invasive diagnostic and therapeutic techniques
Publications
- Assessment of Advanced Diagnostic Bronchoscopy Outcomes for Peripheral Lung Lesions: A Delphi Consensus Definition of Diagnostic Yield and Recommendations for Patient-centered Study Designs. An Official American Thoracic Society/American College of Chest| | View in PubMed
- Education for Tobacco Use Disorder Treatment: Current State, Evidence, and Unmet Needs.| | View in PubMed
- Interventional Pulmonology: Extending the Breadth of Thoracic Care.| | View in PubMed
- COMPLEX PLEURAL SPACES: THE RISKS OF REPEATED THORACENTESIS.| | View in PubMed
- Safety and utility of indwelling pleural catheters in lung transplant recipients.| | View in PubMed
- Medical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World.| | View in PubMed
- Real-World Perspectives and Practices for Pneumonitis/Interstitial Lung Disease Associated With Trastuzumab Deruxtecan Use in Human Epidermal Growth Factor Receptor 2-Expressing Metastatic Breast Cancer.| | View in PubMed
- Impact of a Dedicated Pleural Clinic on Indwelling Pleural Catheter Related Outcomes: A Retrospective Single Center Experience.| | View in PubMed
- Use of tunneled pleural catheters in chronic empyema: Two case reports and brief review of the literature.| | View in PubMed
- Tracheal Reconstruction Using Endotracheal Stent and Pectoralis Major Muscle Flap.| | View in PubMed
- Acquired Benign Tracheoesophageal Fistula: Novel Use of a Nasal Septal Occluder.| | View in PubMed
- Bleeding Risk With Combination Intrapleural Fibrinolytic and Enzyme Therapy in Pleural Infection: An International, Multicenter, Retrospective Cohort Study.| | View in PubMed
- Ambulatory Management of a Recurrent Pneumothorax With an Indwelling Tunneled Pleural Catheter.| | View in PubMed
- Erector Spinae Plane Block: A Novel Anesthetic Approach for Pleuroscopy.| | View in PubMed
- Immunosuppression-Induced Pulmonary Alveolar Proteinosis Following Bilateral Lung Transplantation.| | View in PubMed
- Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology.| | View in PubMed
- Treatment of Advanced-Stage Non-Small Cell Lung Cancer.| | View in PubMed
- Treatment of Early-Stage Non-Small Cell Lung Cancer.| | View in PubMed
- Treatment of Small Cell Lung Cancer.| | View in PubMed
- Keep it Clean: Novel Use of Sterile Disposable Flexible Bronchoscopes for Pleuroscopy.| | View in PubMed
- Lung Cancer Screening.| | View in PubMed
- A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation.| | View in PubMed
- Smoking Cessation and Cancer.| | View in PubMed
- Decreasing 30-day Readmissions for Pleural Effusions after Lung Transplant.| | View in PubMed
- Key Highlights From the American Association for Bronchology and Interventional Pulmonology Evidence-Informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.| | View in PubMed
- AABIP Evidence-informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.| | View in PubMed
- Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.| | View in PubMed
- Abstract 3377: NSCLC subtype-associated molecular and cellular alterations in the normal-appearing bronchial epithelium.| | View in PubMed
- Flexible Bronchoscopic Deployment of a Silicone Bronchial Stent.| | View in PubMed
- Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution.| | View in PubMed
- Indwelling Tunneled Pleural Catheters.| | View in PubMed
- Cryoprobe retrieval of an airway foreign body: A case report and literature review.| | View in PubMed
- Pulmonary Sclerosing Pneumocytoma.| | View in PubMed
- Treatment of persistent bronchopleural fistula with a manually modified endobronchial stent: a case-report and brief literature review.| | View in PubMed
- Bronchoscopic Management of Endobronchial Tumor in Patient With Hemoptysis and Acute Myocardial Infarction.| | View in PubMed
- Impact of acute exposure to cigarette smoke on airway gene expression.| | View in PubMed
- Sarcoidosis With Pleural Effusion as the Presenting Symptom.| | View in PubMed
- Evaluations of Implementation at Early-Adopting Lung Cancer Screening Programs: Lessons Learned.| | View in PubMed
- A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia.| | View in PubMed
- A Call to Formalize Training in Tobacco Dependence Treatment for Pulmonologists.| | View in PubMed
- Translating the transcriptome into tools for the early detection and prevention of lung cancer.| | View in PubMed
- Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention.| | View in PubMed