University of California San Francisco

Simone Kurial headshot
Simone Natalya Thorson Kurial, BSc

Graduate Student

    Biography

    Simone Kurial is a PhD candidate in the Biomedical Sciences program at the University of California, San Francisco. She received her B.Sc. from Brown University, where she trained in the laboratory of Dr. Edith Mathiowitz. Her undergraduate research and honors thesis focused on the optimization of polymer-encapsulated therapeutic compounds for bioavailability. She is currently a member of Dr. Holger Willenbring's laboratory in the Broad Center of Regeneration Medicine and Stem Cell Research where she is investigating mechanisms of hepatocyte transdifferentiation and biliary tree generation as well as targeted gene therapy and translational medicine. Her ultimate goal is to contribute to clinically relevant treatments for diseases of the liver and bile ducts. 

    Simone is certified by the U.S. Department of State for Advanced Fluency in Japanese, and has studied Japanese poetry, literature, film, and mixed media. She hopes to use her language capacity to foster international research collaborations and encourage cultural exchange. 

    Simone is the winner of several creative writing competitions and has a passion for scientific communication; she placed 2nd in the 2024 UCSF Grad Slam competition. She plays African and Afro-Brazilian drums, piano, guitar, and trumpet.

    Education

    Education

    B.Sc. cum honoribus, Biology, Brown University, Providence, RI, 2015

    Fellowships

    Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship (F31), 2020-2021 

    Lloyd M. Kozloff Fellowship, 2020 

    C.R. Bard Undergraduate Research Fellowship, 2014

    Program Affiliations

    Biomedical Sciences (BMS)

    8/2014: Brown University Undergraduate Research Symposium, Providence, R.I., selected poster: "Monitoring the Biodistribution and Toxicity of Nanoparticles in Organ Systems"

    Research Interests

    Liver regeneration 

    Biliary development 

    Transdifferentiation 

    Cholestatic liver diseases 

    Cholangiopathies 

    Organoids 

    Gene therapy 

    High resolution microscopy