University of California San Francisco

Philip Rosenthal, MD

Philip Rosenthal - 144
Philip
Rosenthal
MD

Professor of Pediatrics and Surgery

Director of Pediatric Hepatology Research

Director, Pediatric Hepatology

 

Address

550 16th Street, #4603
San Francisco, CA 94158
United States

Email: [email protected]

Biography

Dr. Rosenthal is the Director of Pediatric Hepatology, Medical Director of the Pediatric Liver Transplant Program and a Professor of Pediatrics and Surgery at the University of California, San Francisco (UCSF). He is board certified in Pediatrics and Pediatric Gastroenterology and has a Certificate of Added Qualification in Transplant Hepatology. Dr. Rosenthal completed his medical training at Downstate Medical Center and the Albert Einstein Medical Center in New York. He then completed a fellowship in pediatric gastroenterology at UCSF. He joined the UCSF faculty in 1995 after serving as Professor of Pediatrics at University of California, Los Angeles (UCLA).

Dr. Rosenthal is a prolific author and a recipient of a number of professional honors and awards and is committed to clinical service, research and education. He has published numerous research articles on hepatitis. Currently, Dr. Rosenthal is pursuing research on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary disease, use of bioartificial liver support utilizing porcine hepatocytes for patients with fulminant liver failure, as well as researching the quality of life following liver transplantation in children.

Dr. Rosenthal’s professional services to the public include television, newspaper and radio interviews on various topics such as hepatitis A, B, and C, and liver transplants for local, national and international audiences. He is consultant to organizations such as the American Liver Foundation, Parents of Kids with Infectious Disease, the Centers for Disease Control and Prevention (CDC), and the National Institute of Health (NIH)

Education

Institution Degree Dept or School End Date
University of California Diversity, Equity, and Inclusion Champion Training 02/2021
SUNY Brooklyn M.D. School of Medicine 1975

Board Certifications

American Board of Pediatrics, General Pediatrics
American Board of Pediatrics, Subspeciality in Pediatric Gastroenterology
American Board of Pediatrics, Certificate of Added Qualification in Transplant Hepatology

Awards & Honors

Award Conferred By Date
Murray Davidson Award American Academy of Pediatrics 2013
Chancellor's Award for Public Service UCSF 2002

Clinical Expertise

Acute Liver Failure
Biliary Atresia
Bioartificial Liver Support
Choledochal Cyst
Cirrhosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Live Donor Liver Transplantation
Liver Transplantation
Neonatal Hepatitis

Program Affiliations

UCSF Helen Diller Family Comprehensive Cancer Center
UCSF Liver Center
Pediatric Liver Transplant Program
Pediatric Intestinal Rehabilitation and Transplantation Program

In the News

Teen Liver Transplant Recipient to Honor Donor at 2013 Rose Parade
December, 28, 2012 | UCSF Transplant Surgery
Father Saves Son by Donating Part of His Liver
October, 01, 2001 | UCSF Transplant Surgery

Grants and Funding

  • Mechanisms of varied sensitivity of P. falciparum field isolates to the antimalarial drug pipeline | NIH | 2018-06-22 - 2028-06-30 | Role: Principal Investigator
  • Childhood Liver Disease Research Network (ChiLDReN) - UCSF (CC) | NIH | 2002-09-15 - 2025-05-31 | Role: Principal Investigator
  • Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in Uganda | NIH | 2020-04-15 - 2025-03-31 | Role: Co-Principal Investigator

Research Narrative

Rosenthal is pursuing research on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary disease, use of bioartificial liver support utilizing porcine hepatocytes for patients with fulminant liver failure, as well as researching the quality of life following liver transplantation in children. 

Clinical Research

Rosenthal is principal investigator on numerous clinical trials including the following:

View all trials 

Research Interests

Bioartificial liver devices

Pediatric Acute Liver Failure (PALF)

Idiopathic neonatal hepatitis

Quality of life after liver transplants

Genetics and immunology of biliary atresia

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 10
  1. Demographic Factors and Biliary Atresia: A Childhood Liver Disease Research Network Study.
    Kastenberg ZJ, Beil CA, Henn L, Alonso EM, Hsu EK, Wang K, Ng VL, Gupta NA, Magee JC, Merion RM, Horslen S, Karpen SJ, Kohli R, Loomes K, Miethke A, Tolliver KM, Rosenthal P, Harpavat S, Sokol RJ, Guthery SL, and the Childhood Liver Disease Research Network (ChiLDReN)| | PubMed
  2. Secondary prophylaxis of variceal hemorrhage in biliary atresia-Analysis of prospective multicenter studies.
    Bass LM, Hawthorne K, Magee JC, Shneider BL, Childhood Liver Disease Research Network (ChiLDReN)| | PubMed
  3. Prospective Multicenter Longitudinal Measurement of Liver Stiffness in School-Age Children With Cholestatic Liver Disease.
    Shneider BL, Goodrich NP, Ye W, Molleston JP, Leung DH, Sokol RJ, Cavallo L, Wang K, Valentino PL, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Miethke AG, Loomes KM, Kohli R, Karpen SJ, Kamath BM, Jensen MK, Bezerra JA, Bass LM, Magee JC, ChiLDReN| | PubMed
  4. Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study.
    Gonzalez-Peralta RP, Wen JW, Hardikar W, Karnsakul WW, Whitworth S, Lin CH, Indolfi G, Rosenthal P, Balistreri W, Schwarz KB, Honegger JR, Zhang X, Svarovskaia EC, Suri V, Kersey K, Leung DH| | PubMed
  5. Placental malaria induces a unique methylation profile associated with fetal growth restriction.
    Ozarslan N, Mong C, Ategeka J, Li L, Buarpung S, Robinson JF, Kizza J, Kakuru A, Kamya MR, Dorsey G, Rosenthal PJ, Gaw SL| | PubMed
  6. Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage.
    Taylor SA, Harpavat S, Gromer KD, Andreev V, Loomes KM, Bezerra JA, Jarasvaraparn C, Wang K, Horslen S, Rosenthal P, Teckman J, Valentino PL, Ng VL, Karpen SJ, Sokol RJ, Alonso EM, Mack CL, Childhood Liver Disease Research Network (ChiLDReN)| | PubMed
  7. Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.
    Luth MR, Godinez-Macias KP, Chen D, Okombo J, Thathy V, Cheng X, Daggupati S, Davies H, Dhingra SK, Economy JM, Edgar RCS, Gomez-Lorenzo MG, Istvan ES, Jado JC, LaMonte GM, Melillo B, Mok S, Narwal SK, Ndiaye T, Ottilie S, Palomo Diaz S, Park H, Peña S, Rocamora F, Sakata-Kato T, Small-Saunders JL, Summers RL, Tumwebaze PK, Vanaerschot M, Xia G, Yeo T, You A, Gamo FJ, Goldberg DE, Lee MCS, McNamara CW, Ndiaye D, Rosenthal PJ, Schreiber SL, Serra G, De Siqueira-Neto JL, Skinner-Adams TS, Uhlemann AC, Kato N, Lukens AK, Wirth DF, Fidock DA, Winzeler EA| | PubMed
  8. Tambjamines as Fast-Acting Multistage Antimalarials.
    Kumar A, Li Y, Dodean RA, Roth A, Caridha D, Madejczyk MS, Jin X, Dennis WE, Lee PJ, Pybus BS, Martin M, Pannone K, Dinh HT, Blount C, Chetree R, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Black C, Sousa J, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Cooper RA, Rottmann M, Orjuela-Sanchez P, Meister S, Winzeler EA, Delves MJ, Matthews H, Baum J, Kirby RW, Burrows JN, Duffy J, Peyton DH, Reynolds KA, Kelly JX, Kancharla P| | PubMed
  9. Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis.
    Jain AK, Busgang SA, Gennings C, Yates KP, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Carpenter D, Fishbein M, Neuschwander-Tetri BA, Tonasia J, Vos MB| | PubMed
  10. Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term.
    Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL| | PubMed