University of California San Francisco

John R. Feiner - 144
John
Feiner
MD

Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Care

Address

521 Parnassus Avenue, #4C1
San Francisco, CA 94117
United States

Email: [email protected]
Fax: 415-476-9516

    Biography

    My research addresses clinical questions by studying human subjects or patients. I collaborate with other faculty in the department on my research and provide expertise in the following areas: data analysis and statistics; mathematical modeling; data acquisition programming; human studies; respiratory physiology.

    My research involvement has included multiple different projects:

    •    Accuracy of pulse oximetry, including determination of methemoglobin, carboxyhemoglobin, and the accuracy of cerebral oximetry.
    •    Organ transplantation and efforts to improve the quality of cadaveric organs.
    •    Acute normovolemic hemodilution to study the tolerance of acute anemia, as a way to examine red cell transfusion thresholds.  Additionally, we have used this model to study other issues in transfusion, including TRALI.
    •    The utility of somatosensory and motor evoked potential, which are used in major spine surgery to assess the integrity of spinal cord function.
    •    The physiology of breathholding and drug-induced apnea.
    •    High altitude physiology
    •    Clinical effects of neuromuscular blockade

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019
    University of California, San Francisco Residency School of Medicine

    Board Certifications

    American Board of Anesthesiology

    Clinical Expertise

    Kidney Transplantation

    Liver Transplantation

    Pancreas Transplantation

    Program Affiliations

    • Department of Anesthesia and Perioperative Care
    • Department of Surgery, Division of Transplantation

    Research Interests

    Hypoxic ventilatory drive at altitude

    Apnea with remifentanil and propofol

    Transfusion Related Acute Lung Injury

    Neuromonitoring in Spine Anesthesia

    Pulse oximeter accuracy

    Physiology of acute anemia

    Predictors of kidney and liver donor organ function

    View Research Profile at UCSF Clinical & Translational Science Institute

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 91
    1. Factors affecting the performance of 5 cerebral oximeters during hypoxia in healthy volunteers.
      Bickler PE, Feiner JR, Rollins MD| | PubMed
    2. Accuracy of the Lifebox pulse oximeter during hypoxia in healthy volunteers.
      Dubowitz G, Breyer K, Lipnick M, Sall JW, Feiner J, Ikeda K, MacLeod DB, Bickler PE| | PubMed
    3. Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation.
      Lewin MR, Bickler P, Heier T, Feiner J, Montauk L, Mensh B| | PubMed
    4. Accuracy of carboxyhemoglobin detection by pulse CO-oximetry during hypoxemia.
      Feiner JR, Rollins MD, Sall JW, Eilers H, Au P, Bickler PE| | PubMed
    5. The effect of deep and awake tracheal extubation on turnover times and postoperative respiratory complications post adenoid-tonsillectomy.
      Menda SK, Gregory GA, Feiner JR, Zwass MS, Ferschl MB| | PubMed
    6. Hemoglobin desaturation after propofol/remifentanil-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers.
      Stefanutto TB, Feiner J, Krombach J, Brown R, Caldwell JE| | PubMed
    7. Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans.
      Weiskopf RB, Feiner J, Toy P, Twiford J, Shimabukuro D, Lieberman J, Looney MR, Lowell CA, Gropper MA| | PubMed
    8. Sex-related differences in the relationship between acceleromyographic adductor pollicis train-of-four ratio and clinical manifestations of residual neuromuscular block: a study in healthy volunteers during near steady-state infusion of mivacurium.
      Heier T, Feiner JR, Wright PM, Ward T, Caldwell JE| | PubMed
    9. High oxygen partial pressure decreases anemia-induced heart rate increase equivalent to transfusion.
      Feiner JR, Finlay-Morreale HE, Toy P, Lieberman JA, Viele MK, Hopf HW, Weiskopf RB| | PubMed
    10. Quantitative tissue oxygen measurement in multiple organs using 19F MRI in a rat model.
      Liu S, Shah SJ, Wilmes LJ, Feiner J, Kodibagkar VD, Wendland MF, Mason RP, Hylton N, Hopf HW, Rollins MD| | PubMed