University of California San Francisco

John R. Feiner - 144
John
Feiner
MD

Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Care

Address

521 Parnassus Avenue, #4C1
San Francisco, CA 94117
United States

Email: [email protected]
Fax: 415-476-9516

    Biography

    My research addresses clinical questions by studying human subjects or patients. I collaborate with other faculty in the department on my research and provide expertise in the following areas: data analysis and statistics; mathematical modeling; data acquisition programming; human studies; respiratory physiology.

    My research involvement has included multiple different projects:

    •    Accuracy of pulse oximetry, including determination of methemoglobin, carboxyhemoglobin, and the accuracy of cerebral oximetry.
    •    Organ transplantation and efforts to improve the quality of cadaveric organs.
    •    Acute normovolemic hemodilution to study the tolerance of acute anemia, as a way to examine red cell transfusion thresholds.  Additionally, we have used this model to study other issues in transfusion, including TRALI.
    •    The utility of somatosensory and motor evoked potential, which are used in major spine surgery to assess the integrity of spinal cord function.
    •    The physiology of breathholding and drug-induced apnea.
    •    High altitude physiology
    •    Clinical effects of neuromuscular blockade

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019
    University of California, San Francisco Residency School of Medicine

    Board Certifications

    American Board of Anesthesiology

    Clinical Expertise

    Kidney Transplantation

    Liver Transplantation

    Pancreas Transplantation

    Clinical Trials

    1. Related Conditions: Hypoxia| Start Date: | End Date:
    2. Related Conditions: Hypoxia| Start Date: | End Date:
    3. Related Conditions: High Altitude| Start Date: | End Date:
    4. Related Conditions: Muscle Relaxation, Sex| Start Date: | End Date:

    Program Affiliations

    • Department of Anesthesia and Perioperative Care
    • Department of Surgery, Division of Transplantation

    Research Interests

    Hypoxic ventilatory drive at altitude

    Apnea with remifentanil and propofol

    Transfusion Related Acute Lung Injury

    Neuromonitoring in Spine Anesthesia

    Pulse oximeter accuracy

    Physiology of acute anemia

    Predictors of kidney and liver donor organ function

    View Research Profile at UCSF Clinical & Translational Science Institute

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 91
    1. Central venous pressure monitoring in living donor kidney recipients does not affect immediate graft function: A propensity score analysis.
      Adelmann D, Bicknell L, Niemann CU, Feiner J, Roll GR, Burdine L, Whitlock EL| | PubMed
    2. Four Types of Pulse Oximeters Accurately Detect Hypoxia during Low Perfusion and Motion.
      Louie A, Feiner JR, Bickler PE, Rhodes L, Bernstein M, Lucero J| | PubMed
    3. Comparison of Transcranial Doppler and Ultrasound-Tagged Near Infrared Spectroscopy for Measuring Relative Changes in Cerebral Blood Flow in Human Subjects.
      Lipnick MS, Cahill EA, Feiner JR, Bickler PE| | PubMed
    4. Effects of Changes in Arterial Carbon Dioxide and Oxygen Partial Pressures on Cerebral Oximeter Performance.
      Schober A, Feiner JR, Bickler PE, Rollins MD| | PubMed
    5. Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations.
      Lieberman JA, Feiner J, Rollins M, Lyon R, Jasiukaitis P| | PubMed
    6. Incidence and Management of Umbilical Artery Flow Abnormalities during Open Fetal Surgery.
      Sinskey JL, Rollins MD, Whitlock E, Moon-Grady AJ, Vu L, Feiner JR, Ferschl MB| | PubMed
    7. Effects of Acute, Profound Hypoxia on Healthy Humans: Implications for Safety of Tests Evaluating Pulse Oximetry or Tissue Oximetry Performance.
      Bickler PE, Feiner JR, Lipnick MS, Batchelder P, MacLeod DB, Severinghaus JW| | PubMed
    8. Evaluating Pulmonary Function: An Assessment of PaO2/FIO2.
      Feiner JR, Weiskopf RB| | PubMed
    9. Tissue Oximetry and Clinical Outcomes.
      Bickler P, Feiner J, Rollins M, Meng L| | PubMed
    10. The Accuracy of 6 Inexpensive Pulse Oximeters Not Cleared by the Food and Drug Administration: The Possible Global Public Health Implications.
      Lipnick MS, Feiner JR, Au P, Bernstein M, Bickler PE| | PubMed