Biography
My research addresses clinical questions by studying human subjects or patients. I collaborate with other faculty in the department on my research and provide expertise in the following areas: data analysis and statistics; mathematical modeling; data acquisition programming; human studies; respiratory physiology.
My research involvement has included multiple different projects:
• Accuracy of pulse oximetry, including determination of methemoglobin, carboxyhemoglobin, and the accuracy of cerebral oximetry.
• Organ transplantation and efforts to improve the quality of cadaveric organs.
• Acute normovolemic hemodilution to study the tolerance of acute anemia, as a way to examine red cell transfusion thresholds. Additionally, we have used this model to study other issues in transfusion, including TRALI.
• The utility of somatosensory and motor evoked potential, which are used in major spine surgery to assess the integrity of spinal cord function.
• The physiology of breathholding and drug-induced apnea.
• High altitude physiology
• Clinical effects of neuromuscular blockade
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California | Diversity, Equity, and Inclusion Champion Training | 2019 | |
University of California, San Francisco | Residency | School of Medicine |
Board Certifications
American Board of Anesthesiology
Clinical Expertise
Kidney Transplantation
Liver Transplantation
Pancreas Transplantation
Clinical Trials
- Accuracy of BabySat V3 With Profound Hypoxia and Motion (NCT05581394)Related Conditions: Hypoxia| Start Date: | End Date:
- Related Conditions: Hypoxia| Start Date: | End Date:
- Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude (NCT02233582)Related Conditions: High Altitude| Start Date: | End Date:
- Related Conditions: Muscle Relaxation, Sex| Start Date: | End Date:
Program Affiliations
- Department of Anesthesia and Perioperative Care
- Department of Surgery, Division of Transplantation
In the News
Research Interests
Hypoxic ventilatory drive at altitude
Apnea with remifentanil and propofol
Transfusion Related Acute Lung Injury
Neuromonitoring in Spine Anesthesia
Pulse oximeter accuracy
Physiology of acute anemia
Predictors of kidney and liver donor organ function
View Research Profile at UCSF Clinical & Translational Science Institute
Publications
- In Response.| | PubMed
- Open Access Data Repository and Common Data Model for Pulse Oximeter Performance Data.| | PubMed
- The performance of 11 fingertip pulse oximeters during hypoxemia in healthy human participants with varied, quantified skin pigment.| | PubMed
- Low Perfusion and Missed Diagnosis of Hypoxemia by Pulse Oximetry in Darkly Pigmented Skin: A Prospective Study.| | PubMed
- Quantifying pulse oximeter accuracy during hypoxemia and severe anemia using an in vitro circulation system.| | PubMed
- Reducing Volatile Anesthetic Waste Using a Commercial Electronic Health Record Clinical Decision Support Tool to Lower Fresh Gas Flows.| | PubMed
- Frequency, Method, Intensity, and Health Sequelae of Sexual Choking Among U.S. Undergraduate and Graduate Students.| | PubMed
- Pulse Oximeter Performance, Racial Inequity, and the Work Ahead.| | PubMed
- Perioperative Normal Saline Administration and Delayed Graft Function in Patients Undergoing Kidney Transplantation: A Retrospective Cohort Study.| | PubMed
- Anesthesia for Maternal-Fetal Interventions: A Survey of Fetal Therapy Centers in the North American Fetal Therapy Network.| | PubMed