Biography
Kukreja is the associate director of UCSF's lung transplant research division of cardiothoracic surgery.
Kukreja earned a medical degree at the David Geffen School of Medicine at UCLA. She completed residencies in general surgery at Brigham and Women's Hospital in Boston and in cardiothoracic surgery at UCSF. She completed fellowships in general surgery and thoracic surgery at Brigham and Women's Hospital, and also completed extensive training in designing clinical trials, studies that evaluate potential treatments' safety and efficacy. She has a master's degree in public health from the Harvard T.H. Chan School of Public Health.
Kukreja has received many professional honors, including the Pharmacia/Upjohn Trauma Research Competition Award, John A. Mannick Research Award and an excellence in teaching award from Harvard Medical School.
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California | Diversity, Equity, and Inclusion Champion Training | 2018 | |
University of California Los Angeles | M.D. | School of Medicine | 1994 |
University of California, San Francisco | Postdoctoral Studies | Graduate Division |
Board Certifications
American Board of Surgery, General Surgery
American Board of Thoracic Surgery, Thoracic and Cardiac Surgery
Clinical Expertise
Bronchioloalveolar Carcinoma (BAC)
Carcinoid Tumors
Chest Wall Tumors
Esophageal Cancer
Esophagectomy
Lung Metastases
Lung Transplantation
Lung Volume Reduction Surgery
Malignant Mesothelioma
Mediastinal Masses
Minimally Invasive Thoracic Surgery
Non-Small Cell Lung Cancer
Sarcomas
Small-Cell Lung Cancer
Tracheal Tumors
Video-Assisted Thoracoscopic Surgery (VATS)
Clinical Trials
- Related Conditions: Lung Transplant| Start Date: | End Date:
- 10°C vs 4°C Lung Preservation RCT (NCT05898776)Related Conditions: Lung Transplant, Transplants, Organ Preservation| Start Date: | End Date:
- OCS Lung System EXPAND II Trial (NCT03343535)Related Conditions: Lung Transplant| Start Date: | End Date:
- International EXPAND Lung Pivotal Trial (NCT01963780)Related Conditions: Lung Transplant, Transplants| Start Date: | End Date:
Program Affiliations
Thoracic Oncology Program, UCSF Helen Diller Family Comprehensive Cancer Center
Lung Transplantation, UCSF Heart and Lung Transplantation Program
San Francisco Veterans Administration Hospital
Contra Costa Regional Medical Center
In the News
Research Interests
- Novel therapies for lung cancer
- Clinical trials for new surgical modalities
Publications
- Disturbed sleep after lung transplantation is associated with worse patient-reported outcomes and chronic lung allograft dysfunction.| | View in PubMed
- MICB Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death.| | View in PubMed
- CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury.| | View in PubMed
- Outcomes of Lung Transplantation for Idiopathic Pulmonary Fibrosis: Glass Half Full or Still Half Empty?| | View in PubMed
- Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction.| | View in PubMed
- Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis.| | View in PubMed
- Prone Positioning After Lung Transplantation Remains Prone to Debate.| | View in PubMed
- Management of primary graft dysfunction after lung transplantation with extracorporeal life support: an evidence-based review.| | View in PubMed
- Biofire pneumonia panel in lung donors: faster detection but limited pathogens.| | View in PubMed
- The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation.| | View in PubMed
- Regadenoson Is All the RAGE: Targeting the Inflammatory Cascade in Primary Graft Dysfunction.| | View in PubMed
- Perioperative Fluid Management.| | View in PubMed
- Lung preservation: from perfusion to temperature.| | View in PubMed
- Development of the Lung Transplant Frailty Scale (LT-FS).| | View in PubMed
- Lungs Preserved on Ice or in a Refrigerator? Prolonged Static Lung Storage at 10 °C.| | View in PubMed
- Subphenotypes of frailty in lung transplant candidates.| | View in PubMed
- Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function.| | View in PubMed
- The Lung Allocation Score Remains Inequitable for Patients with Pulmonary Arterial Hypertension, Even after the 2015 Revision.| | View in PubMed
- Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.| | View in PubMed
- CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction.| | View in PubMed
- Frailty and genetic risk predict fracture after lung transplantation.| | View in PubMed
- Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease.| | View in PubMed
- NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes.| | View in PubMed
- The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation.| | View in PubMed
- Intercostal Nerve Cryoanalgesia Versus Thoracic Epidural Analgesia in Lung Transplantation: A Retrospective Single-Center Study.| | View in PubMed
- Contemporary trends in PGD incidence, outcomes, and therapies.| | View in PubMed
- ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.| | View in PubMed
- Chronic Lung Allograft Dysfunction.| | View in PubMed
- Early Postoperative Management of Lung Transplant Recipients.| | View in PubMed
- Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.| | View in PubMed
- Inflammation on bronchoalveolar lavage cytology is associated with decreased chronic lung allograft dysfunction-free survival.| | View in PubMed
- Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses.| | View in PubMed
- Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction.| | View in PubMed
- Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.| | View in PubMed
- Lung Transplantation for Patients With COVID-19.| | View in PubMed
- ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part III: Pharmacology, medical and surgical management of post-transplant extrapulmonary conditions statements.| | View in PubMed
- Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis.| | View in PubMed
- The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation.| | View in PubMed
- Lung transplantation from swimming pool drowning victims: A case series.| | View in PubMed
- Rapid molecular detection of airway pathogens in lung transplant recipients.| | View in PubMed
- Mobile health technology to improve emergent frailty after lung transplantation.| | View in PubMed
- Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury.| | View in PubMed
- Complement activation on endothelium initiates antibody-mediated acute lung injury.| | View in PubMed
- Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction.| | View in PubMed
- An Analysis of Successful Features of Anesthesiology Journal Clubs.| | View in PubMed
- Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.| | View in PubMed
- Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection.| | View in PubMed
- Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States.| | View in PubMed
- Lung transplant programs in developing countries: challenges, solutions, and outcomes.| | View in PubMed
- Redefining marginality: donor lung criteria.| | View in PubMed
- Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study.| | View in PubMed
- Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.| | View in PubMed
- Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.| | View in PubMed
- Donor heart and lung procurement: A consensus statement.| | View in PubMed
- Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis.| | View in PubMed
- Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study.| | View in PubMed
- Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.| | View in PubMed
- Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.| | View in PubMed
- Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death.| | View in PubMed
- Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study.| | View in PubMed
- Portable normothermic ex-vivo lung perfusion, ventilation, and functional assessment with the Organ Care System on donor lung use for transplantation from extended-criteria donors (EXPAND): a single-arm, pivotal trial.| | View in PubMed
- A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates.| | View in PubMed
- Management and clinical outcomes after lung transplantation in patients with pre-transplant Mycobacterium abscessus infection: A single center experience.| | View in PubMed
- Development and Preliminary Validation of the Lung Transplant Quality of Life (LT-QOL) Survey.| | View in PubMed
- Time-efficient, goal-directed, and evidence-based teaching in the ICU.| | View in PubMed
- Gene signatures common to allograft rejection are associated with lymphocytic bronchitis.| | View in PubMed
- Frailty trajectories in adult lung transplantation: A cohort study.| | View in PubMed
- NKG2C Natural Killer Cells in Bronchoalveolar Lavage Are Associated With Cytomegalovirus Viremia and Poor Outcomes in Lung Allograft Recipients.| | View in PubMed
- Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib.| | View in PubMed
- Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.| | View in PubMed
- Genotypes associated with tacrolimus pharmacokinetics impact clinical outcomes in lung transplant recipients.| | View in PubMed
- Surgical Management of Pulmonary Mucormycosis in Third-Trimester Pregnancy.| | View in PubMed
- A mobile health technology enabled home-based intervention to treat frailty in adult lung transplant candidates: A pilot study.| | View in PubMed
- Suppressed calcineurin-dependent gene expression identifies lung allograft recipients at increased risk of infection.| | View in PubMed
- Frailty phenotypes and mortality after lung transplantation: A prospective cohort study.| | View in PubMed
- Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.| | View in PubMed
- Elevated donor plasminogen activator inhibitor-1 levels and the risk of primary graft dysfunction.| | View in PubMed
- Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation.| | View in PubMed
- Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness.| | View in PubMed
- Report of the ISHLT Working Group on primary lung graft dysfunction Part IV: Prevention and treatment: A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation.| | View in PubMed
- Discharge against Medical Advice in Surgical Patients with Posttraumatic Stress Disorder: A Case Report Series Illustrating Unique Challenges.| | View in PubMed
- HLA Mismatching Favoring Host-Versus-Graft NK Cell Activity Via KIR3DL1 Is Associated With Improved Outcomes Following Lung Transplantation.| | View in PubMed
- Short lung transplant donor telomere length is associated with decreased CLAD-free survival.| | View in PubMed
- Adverse outcomes associated with pulmonary hypertension in chronic obstructive pulmonary disease after bilateral lung transplantation.| | View in PubMed
- Protein biomarkers associated with primary graft dysfunction following lung transplantation.| | View in PubMed
- Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study.| | View in PubMed
- Donor-Reactive Regulatory T Cell Frequency Increases During Acute Cellular Rejection of Lung Allografts.| | View in PubMed
- Serotonin Syndrome Following an Uncomplicated Orthopedic Surgery in a Patient With Post-Traumatic Stress Disorder.| | View in PubMed
- miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis.| | View in PubMed
- Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation.| | View in PubMed
- Prolonged Barium-Impaction Ileus in Two Lung Transplant Recipients With Systemic Sclerosis: Case Report.| | View in PubMed
- Voriconazole Exposure and Risk of Cutaneous Squamous Cell Carcinoma, Aspergillus Colonization, Invasive Aspergillosis and Death in Lung Transplant Recipients.| | View in PubMed
- Lung transplantation for hypersensitivity pneumonitis.| | View in PubMed
- Clinical outcomes of lung transplant recipients with telomerase mutations.| | View in PubMed
- Body composition and mortality after adult lung transplantation in the United States.| | View in PubMed
- Belatacept for Maintenance Immunosuppression in Lung Transplantation.| | View in PubMed
- Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis.| | View in PubMed
- Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer.| | View in PubMed
- Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity.| | View in PubMed
- The feasibility of lung transplantation in HIV-seropositive patients.| | View in PubMed
- Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma.| | View in PubMed
- Pulmonary interstitial emphysema in adults: a clinicopathologic study of 53 lung explants.| | View in PubMed
- Bronchoalveolar lavage cell immunophenotyping facilitates diagnosis of lung allograft rejection.| | View in PubMed
- Development and validation of a lung transplant-specific disability questionnaire.| | View in PubMed
- Extracorporeal life support for acute respiratory distress syndromes.| | View in PubMed
- Outcomes in systemic sclerosis-related lung disease after lung transplantation.| | View in PubMed
- Preoperative CT-Guided percutaneous wire localization of ground glass pulmonary nodules with a modified Kopans wire.| | View in PubMed
- A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directions.| | View in PubMed
- Scedosporium prolificans pericarditis and mycotic aortic aneurysm in a lung transplant recipient receiving voriconazole prophylaxis.| | View in PubMed
- Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation.| | View in PubMed
- Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis.| | View in PubMed
- Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives.| | View in PubMed
- Outcomes for lung transplantation for lung cancer in the United Network for Organ Sharing Registry.| | View in PubMed
- The 4G/4G genotype of the PAI-1 (serpine-1) 4G/5G polymorphism is associated with decreased lung allograft utilization.| | View in PubMed
- Survival following lung transplantation for silicosis and other occupational lung diseases.| | View in PubMed
- Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation.| | View in PubMed
- Posterior glenohumeral joint dislocation: a rare complication of central venous cannulation in a patient undergoing coronary artery surgery.| | View in PubMed
- Sudden onset of atrial flutter during continuous venovenous hemodialysis.| | View in PubMed
- Epidemiology of non-small cell lung cancer in Asian Americans: incidence patterns among six subgroups by nativity.| | View in PubMed
- Malignant pleural mesothelioma: overview of the North American and European experience.| | View in PubMed
- Occult breast carcinoma in reduction mammaplasty specimens: 14-year experience.| | View in PubMed
- Section IV: selective use of neoadjuvant therapy.| | View in PubMed